7/1/20 – 30/3/21
Episode Listing
- S22 E1 (7 Jan 20) by Patrick Homes
- S22 E2 (15 Jan 20) by Katie Douglas
- S22 E3 (21 Jan 20) by Katie Douglas
- S22 E4 (28 Jan 20) by Davey Jones
- S22 E5 (5 Feb 20) by Nick Fisher
- S22 E6 (11 Feb 20) by Claire Miller
- S22 E7 (18 Feb 20) by Johanne McAndrew & Elliot Hope
- S22 E8 (25 Feb 20) by Alex Straker
- S22 E9 (26 Feb 20) by Damian Mullen
- S22 E10 (10 Mar 20) by Isla Gray
- S22 E11 (24 Mar 20) by Ed Sellek
- S22 E12 (31 Mar 20) by Ed Sellek
- S22 E13 (7 Apr 20) by Simon Norman
- S22 E14 (14 Apr 20) by Joe Ainsworth
- S22 E15 (2 Jun 20) by Becky Prestwich
- S22 E16 (9 Jun 20) by Phil Mulryne
- S22 E17 (16 Jun 20) by Johnny Candon
- S22 E18 (23 Jun 20) by Katie Douglas
- S22 E19 (30 Jun 20) by Katie Douglas
- S22 E20 (7 Jul 20) by Julie Parsons
- S22 E21 (14 Jul 20) by Ed Sellek
- S22 E22 (21 Jul 20) by Davey Jones
- S22 E23 (28 Jul 20) by Nick Fisher
- S22 E24 (4 Aug 20) by Lucia Haynes
- S22 E25 (11 Aug 20) by Joe Ainsworth
- S22 E26 (10 Nov 20) by Patrick Homes
- S22 E27 (17 Nov 20) by Joe Ainsworth
- S22 E28 (24 Nov 20) by Ciara Conway
- S22 E29 (1 Dec 20) by Andy Bayliss
- S22 E30 (8 Dec 20) by Ed Sellek
- S22 E31 (15 Dec 20) by Damian Mullen
- S22 E32 (5 Jan 21) by Katie Douglas
- S22 E33 (12 Jan 21) by Rebekah Harrison
- S22 E34 (19 Jan 21) by Patrick Homes
- S22 E35 (26 Jan 21) by Joe Ainsworth
- S22 E36 (2 Feb 21) by Joe Ainsworth
- S22 E37 (10 Feb 21) by Ciara Conway
- S22 E38 (16 Feb 21) by Ciara Conway
- S22 E39 (23 Feb 21) by Michelle Lipton
- S22 E40 (2 Mar 21) by Becky Prestwich
- S22 E41 (9 Mar 21) by Katie Douglas
- S22 E42 (16 Mar 21) by Andy Bayliss
- S22 E43 (23 Mar 21) by Ed Sellek
- S22 E44 (30 Mar 21) by Lydia Marchant
Joining Cast
- S22 E12 Louis McGerry – Staff Nurse
- S22 E13 Guy Self –
- S22 E26 Josh Hudson – F1
- S22 E26 Jeong Soo-Han – F1
- S22 E26 Skylar Bryce – F1
- S22 E26 Alex Duval – Healthcare Assistant (* played by a different actor in S20 E41/42)
- S22 E28 Lucky Simpson – Psychiatric Nurse
- S22 E37 Kylie Madden – Staff Nurse
- S22 E37 Sahira Shah – Consultant Cardiothoracic surgeon
Regular Cast
- Henrik Hanssen – Consultant General Surgeon/ CEO
- Maxine McGerry – Consultant Neurosurgeon, Temp CEO
- Ange Godard – Consultant Pediatrician/ General Surgeon, clinical lead (YAU)
- Kian Madani – Consultant Cardiothoracic surgeon
- Sacha Levy – Specialist Registrar, General Surgery
- Chloe Godard – ST5 doctor, Cardiothoracic Surgery
- Dominic Copeland – ST5 doctor, General Surgery
- Fletch – Director of Nursing Services
- Donna Jackson – Senior Staff Nurse
Exiting Cast
- S22 E3 Serena Campbell – Consultant General Surgeon
- S22 E11 Ben Sherwood – Locum Consultant General Surgery
- S22 E14 Xavier ‘Zav’ Duval – ST6 doctor, General Surgery
- S22 E25 Estelle Harrison – Senior Staff Nurse/ Transplant Co-Ordinator
- S22 E25 Guy Self
- S22 E26 Ric Griffin – Consultant General Surgeon
- S22 E36 Jac Naylor – Consultant Cardiothoracic Surgeon
- S22 E40 Alex Duval – Healthcare Assistant
- S22 E41 Skylar Bryce – F1
- S22 E43 Cameron Dunn – CT1 doctor, General Surgery
- S22 E44 Nicky McKendrick – CT1 doctor, Cardiothoracic surgery, junior doctor lead
Cast Guest Return
- S22 E22 Raf Di Lucca
Major Guest Characters
Notable Guest Stars
Casualty/ Holby City Guest Appearances
Casualty Crossovers
- S22 E2 Marty Kirkby
- S22 E12/13 David Hide
